小弟我下传不了文件

我上传不了文件
我在试上传文件，出现错误：
Warning: move_uploaded_file(upload/201006202127103745.png): failed to open stream: No such file or directory in E:\www\login\upload.php on line 28 Warning: move_uploaded_file(): Unable to move 'C:\WINDOWS\Temp\php89.tmp' to 'upload/201006202127103745.png' in E:\www\login\upload.php on line 28 save picture failed
我的代码：
if($_SERVER['REQUEST_METHOD']=='POST')
{
  if(!is_uploaded_file($_FILES['file']['tmp_name']))
  {
  echo "fasgsdf";
  exit;
  }
   
  if((($_FILES["file"]["type"]=="image/gif")||
  ($_FILES["file"]["type"]=="image/jpeg")||
  ($_FILES["file"]["type"]=="image/jpg")||
  ($_FILES["file"]["type"]=="image/gif")||
  ($_FILES["file"]["type"]=="image/png")||
  ($_FILES["file"]["type"]=="image/bmp"))&& ($_FILES["file"]["size"]   {
  if(file_exists("upload/".$_FILES["file"]["name"]))
  {
  echo "picture already exist";
  }
  else
  {  
  $result=move_uploaded_file($_FILES["file"]["tmp_name"],"upload/".$_FILES["file"]["name"]);
  if($result)
  echo "save picture fuccessful";
  else
  echo "save picture failed";
  }
  }
  else
  {
  echo "invalid file";
  exit;
  }
}
?>
html部分：
  <script><br /> function uploadpic()<br /> {<br /> var form=document.getElementById("form1");<br /> form.submit();<br /> }<br /> </script>